ADMET
Bertin Pharma offers a full and comprehensive range of drug metabolism and pharmacokinetic studies in support of drug candidate selection to regulatory submission.
We can evaluate the
metabolic and pharmacokinetic characteristics of chemical entities and biotechnology compounds and provide you with a range of customized services to characterize their ADMET (Absorption, Distribution, Metabolism, Excretion, Toxicity)properties.
Our laboratories are GLP and our highly trained scientific staff (including pharmacokineticists, biochemists, bioanalytical chemists, immunoanalysts) offer both standard study designs and innovative approaches dedicated to your unique drug development issues.
Our senior scientists have experience as study directors and principal investigators offering a high quality studies and reports along with expert consultation.
Our range of services will help you find solutions in the following fields:
Your advantages for working with us
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Narrowing efficiently the possible drug candidates
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Numerous studies already performed for big pharma, European SMEs & biotech companies
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Large analytical & technological platform
s
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Dedicated & state-of-the-art platforms
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Custom expertise in accordance with FDA, EMEA and ICH note of guidance or guidelines (GLP-compliant studies)
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Answering EMA & FDA regulations
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Mix of CEA/Bertin Pharma teams allowing pioneer & state of the art expertise
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A solid background in set-up & validation of EIA (more than 500 assays)
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Numerous animal & cell models
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ADMET equipment platform
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HPLC-MS: ESI, APCI, tandem quadrupole, Q-tof, orbitrap, maldi-tof & ion trap analyzers
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HPLC: UV, fluorescence & radiodetection
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Pharmacokinetic softwares
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Automated sample preparation platform for solid phase, liquid-liquid extractions
& turbulent flow
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Automated on-line and solid phase extraction
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Automated blood sampling: Culex®
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Rodent facilities including GMOs
If you wish more details about our ADME services, feel free to contact us
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Our
other
services
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Biotransformation
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Biomarkers
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Pharmacology
